Erectile dysfunction is also referred to as sexual impotence and it is a type of sexual dysfunction. In this condition, men are unable to keep an erection of the penis during sex even when he has the sexual urge. It occurs because of low or restricted blood supply to penis. Thus, the achieved erection is too soft or doesn’t last long for penetration. Kamagra Gold enhances the blood supply to the penile region and is commonly prescribed by doctors all around the world.
The symptoms are not very obvious however it might include:
- low sexual desire
- trouble getting and keeping an erection
Many risks factor, psychological and medical condition collectively leads to erectile dysfunction in men and they are the following:
- diabetes, heart disease, obesity
- stress, anxiety, depression, relationship problem
- high blood pressure, metabolic syndrome
- sleep disorder, alcoholism, tobacco use
Always communicate about this with your partner as many men usually do not address this problem. It can affect the relationship of the couple by causing stress and low self-confidence in men.
Action Mechanism of sildenafil:
This drug is not effective without sexual stimulation however; with sexual stimulation; its’ drug action mechanism
Sildenafil tablet when consumed orally, the drug is quickly absorbed. It is metabolized primarily with the help of CYP3A4 hepatic microsomal isoenzymes.
With the help of sexual stimulation, its action mechanism is performed. It releases of nitric oxide (NO) in the corpus cavernosum. This activates guanylate cyclase enzyme and increases cyclic guanosine monophosphate (cGMP) level. This improves inflow of blood and smooth muscle relaxation in the corpus cavernosum.
It selective inhibits cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP.
Upon the activation of NO/cGMP pathway, along with sexual stimulation, inhibition of PDE5 occurs. It results in increased corpus cavernosum levels of cGMP. Therefore sexual stimulation is necessary in order for the drug to produce its intended beneficial effects.
Benefits of sildenafil (Kamagra Gold)
There are several studies that have proved the potency and benefits of the drug. It is mostly favoured by the doctors all around the world. It has safety profile and is used to treat other medical condition as well and they are the following:
- It is used in the treatment of pulmonary hypertension.
- It is also used in the treatment of mountain sickness.
- Heart disease is also treated, like congestive heart failure, diastolic dysfunction and stroke.
- It is also used to treat benign prostatic hyperplasia also known as prostate gland enlargement.
It is well tolerated and safe for the patients in the management of erectile dysfunction. This will bring confidant and comfort environment, restoring the sexual life and bringing the pleasure of love in your life back again.
Dosage and storage of sildenafil (Kamagra Gold)
Kamagra Gold is available in different dosage strength and formulations. At BuyUrMed, it is available in the following formulations and strengths:
- Tablets - 25 mg
- Tablets - 50 mg
- Tablets - 100 mg
Please note that the drug offers no protection against sexually transmitted diseases and it must be taken only with the physicians’ consultation.
- Store at 25°C (77°F) and excursions permitted from 15°C to 30°C (59°F to 86°F).
- Keep it away from children and pet’s reach and sight.
- Keep it safely in an air-tight container.
- Store it away from moisture and heat.
- Always check the expiry date.
- Avoid throwing away the medicine along the household waste carelessly.
Precautions while taking sildenafil (Kamagra Gold)
- If you have any allergy to sildenafil or inactive component of the drug you should report to your doctor.
- Before taking it, tell your doctor if you ever had heart problems stroke in the past 6 months such as kidney disease, liver disease, high or low blood pressure, a severe loss of body water.
- It is also essential that you consult with your doctor if you have condition like penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision)
- Caution is advised if it is administrated along with any alpha blockers, ritonavir, other PDE5 Inhibitors, nitrate-based drugs like nitro-glycerine, guanylate cyclase stimulators such as riociguat
- Avoid alcohol consumption and use of marijuana as it can cause vision problem and dizziness.
- Tell your doctor that you are taking this medication before having any surgery even if its’ simply dental.
- Unless clearly asked by their doctor, pregnant women are not recommended to use it and must discuss the benefits and risks of the medication.
- This medication passes into breast milk in small amounts, so always consult with your doctor before breastfeeding.
Side Effects of sildenafil (Kamagra Gold)
The most common side effects include the following:
- bloody and cloudy urine
- impaired vision
- impaired hearing
- painful urination
- sensitivity to light
- painful and prolonged erection
- stuffy nose
- breathing problems
- trouble sleeping
- muscle pain
The rare side effects include the following:
- sore throat
- skin rash
- eye pain
- rectal bleeding
If any of the above-mentioned side effects persist or worsen please inform your doctor immediately. Or if you also notice other effects not listed above report to the doctor.