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Erectile dysfunction can be described as the persistent inability to achieve and sustain an erection through the duration of sex. A loss of interest in sex can also be classified as sexual impotence or ED. The risks of erectile dysfunction increase with age as the arteries that supply blood to the penis become narrower. Erectile dysfunction can occur in men of all ages, however frequent occurrence of ED can be a sign of a more serious illness. ED has been linked to cardiovascular diseases, diabetes, high cholesterol levels and high blood pressure. Excess alcohol consumption, smoking or drug addiction can also be causes of sexual impotence in men. If you suffer from any of the symptoms of ED, it is recommended that you consult a qualified physician to examine and determine that exact cause of ED. However, some of the common reasons associated with ED are listed as below:

  • Anxiety
  • High blood pressure
  • Cardiovascular ailments
  • High cholesterol
  • Surgeries or treatments
  • Medicine side-effects
  • Obesity
  • Consumption of drugs
  • Consumption of alcohol
  • Smoking 

In addition, psychological or physiological causes can also result in ED. One of the most widely recommended medications for ED is Viagra, sildenafil.

Action Mechanism of sildenafil citrate

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During sexual arousal, nitric oxide (NO) is released into the corpus cavernosum of the penis. This activates the enzyme guanylate cyclase, which leads to a rise in the levels of cyclic guanosine monophosphate (cGMP). cGMP helps in the smooth muscle relaxation in the corpus cavernosum which leads to a higher supply of blood to the penis resulting in a rigid and healthy erection. However, cGMP-specific phosphodiesterase type 5 (PDE5) reduces its effects by the degradation of cGMP. Sildenafil medicine is a PDE5 inhibitor that enhances the effect of NO leading to higher cGMP levels and erection through smooth muscle relaxation. It does not have a direct effect on cGMP levels i.e. it cannot lead to an erection without sexual stimulation.

In certain cases, this medication is also prescribed to treat pulmonary arterial hypertension (PAH) but it must be taken only with the physicians’ consultation.

Benefits of sildenafil citrate (Viagra)

  • Sildenafil medicine is a very efficient cGMP-specific PDE5 inhibitor.
  • Along with sexual stimulation, it increases the blood flow to the penis helping in achieving a healthy erection.
  • Viagra is a small blue pill and is taken by oral administration. If taken 1 hour before sexual activity, it is effective for up to 4 hours with a bioavailability of 40%.
  • It has also been used to treat pulmonary arterial hypertension (PAH), however, it must not be administered without a recommendation from a physician.

Dosage and storage of sildenafil citrate  (Viagra)

 Dosage:

Sildenafil is sold under the brand name Viagra.

This medication is available in various dosage formulations and strengths. At BuyUrMed, they are available as film coated tablets in the formulation of 100 mg.

The above dosage should be taken as per the physicians’ recommendation however; no more than 1 tablet should be taken per day.

Storage:

  • You must store this medication away from moisture, in an airtight container.
  • If you buy sildenafil online, do not consume a tablet if the packaging has been tampered with.
  • You must ensure that the medication is kept out of reach of pets and children at home.
  • Store the tablets within the temperature range of 15° to 30°C (59° to 86°F) or the nearest possible temperatures.
  • Always ensure that this medication is stored away from direct sunlight and avoid exposure to heat.

Precautions while taking sildenafil citrate (Viagra)

  •  Sildenafil tablets are not recommended for patients undergoing treatment for heart ailments and especially for those who are prescribed nitrate-based drugs.
  • Also, it should not be taken in combination with other PDE5 inhibitors as this may lead to adverse side-effects.
  • If a user experiences Priapism i.e. an erection lasting for more than 4 hours after taking sildenafil tablets, then they must seek immediate medical assistance.
  • Patients with high blood pressure are advised to practice caution while taking this medication as it may cause abnormal blood pressure levels.
  • Do not combine this medication with other drugs like poppers as it can cause severe side-effects and complications.
  • Also, Viagra should never be combined with other medications.

Side-effects of sildenafil citrate (Viagra)

Like all medication, this one too poses side-effects. Some of the common side-effects are listed as below:Sildenafil, sildenafil 100mg, sildenafil online, sildenafil citrate 100mg, buy sildenafil, sildenafil tablets, sildenafil price, sildenafil 50 mg, Sildenafil 100, sildenafil dosage, buy sildenafil online, sildenafil 100mg price, sildenafil cost, where to buy sildenafil, sildenafil 100 mg tablet, sildenafil side effects, sildenafil pills, sildenafil 50 mg price, sildenafil 100mg cost, order sildenafil online, sildenafil medication, buy sildenafil 100mg, sildenafil 100mg online, sildenafil uk, generic sildenafil 100mg, sildenafil uses, sildenafil medicine, buy sildenafil uk

  • Dizziness
  • Nasal congestion
  • Dyspepsia
  • Flushing
  • Headache

If any of the above reactions last longer than usual, you must seek immediate medical help.

The administration of Viagra has also been met with some severe side-effects such as:

  • Loss of vision in the eye because of low blood pressure
  • Ringing of ears or loss of hearing
  • Irregular heartbeats or palpitations
  • An erection lasting more than 4 hours

If you experience any of these, you must contact your doctor immediately or seek urgent medical assistance!

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